Document Type
Article
Publication Date
2019
Department
Biology
Language
English
Publication Title
CourseSource
Abstract
A common polymorphism in the alpha-actinin-3 (ACTN3) gene results in the lack of ACTN3 protein expression in fast twitch muscle fibers in ~16% of the human population (1). This genetic change has been linked with muscle performance in humans (2) but does not cause any known muscle disease (1). We have developed a series of laboratory modules that provide an authentic classroom research experience and which address the connection between science and society by examining the implications of ACTN3 genetic testing to improve sports training and performance. This article accompanies the lesson "The ACTN3 Polymorphism: Applications in Genetics and Physiology Teaching Laboratories," and summarizes background information that an instructor would need to implement the project in class.
DOI
10.24918/cs.2019.31
Recommended Citation
Somers, Dana J., Tiffany A. Frey, and Heather L. Lehman. "The Science Behind the ACTN3 Polymorphism." CourseSource (2019). https://www.coursesource.org/courses/the-science-behind-the-actn3-polymorphism#tabs-0-content=1
Comments
This published version is made available on Dickinson Scholar with the permission of the publisher. For more information on the published version, visit CourseSource's Website.
Copyright: © 2019Somers, Frey, and Lehman. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original author and source are credited.